The aim of this commentary is to discuss from a rehabilitation perspective the Cochrane Review “Bone modifying agents for reducing bone loss in women with early and locally advanced breast cancer: a network meta-analysis” by Adams et al., published by the Cochrane Breast Cancer Group. This Cochrane Corner is produced in agreement with Journal of Musculoskeletal and Neuronal Interactions by Cochrane Rehabilitation with views of the review summary author in the “implications for practice” section.